E ERVAtlas

Human blood immune-cell ERV/TE reference

ERVAtlas

A confound-aware atlas, not an aging-clock claim.

Explore single-cell, locus-resolved endogenous retrovirus and transposable-element expression across human blood immune cell types and donor age, built from 84 donors and 9 immune cell types.

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84donors
9cell types
90age tests
0partial FDR<0.10

Reference matrix: donor × cell type × ERV/TE family, with explicit confound control.

Read this before interpreting any association. Of 90 cell-type × ERV-family age associations tested, 0 pass FDR<0.10 on raw correlation and 0 pass FDR<0.10 after controlling for sequencing depth and cell count. This atlas does not describe a validated ERV aging clock. The robust signal in this cohort is CMV serostatus ↔ inflammaging (r=0.53, p=4e-9), reported here as a resource for further research.
What you can do

Three entry points for a reusable reference resource

Browse the confound-controlled tables, compare your pseudobulk matrix, or download the underlying reference files with provenance.

01

Browse associations

Inspect age and CMV association tables with explicit artifact flags after confound control.

Open browser →
02

Compare your data

Upload a small pseudobulk ERV/TE matrix and compute reference percentiles in memory.

Run comparison →
03

Methods & provenance

Read the data dictionary, caution notes, and field definitions behind every number.

Read methods →
Downloads

Reference files

All downloadable files are provided as a noncommercial research resource. Please cite the reference cohort.

Age associationsCSV · family × cell type CMV top featuresCSV · inflammaging signal Reference matrixParquet · pseudobulk Immune subtype ageCSV · subtype tests Inflammaging modulesJSON · gene sets Data dictionaryMarkdown · provenance